Lena Friberg was in 2014 promoted to Professor of Pharmacometrics and is since 2021 Professor of Pharmacokinetics and Pharmacodynamics. Her research focuses on translation and dose optimization within oncology and infectious diseases, by advancing concepts for interpretation and integration of in vitro, in vivo and clinical data through PKPD-modelling. Developed methodology facilitates transition between drug development stages while considering both desired and adverse effects.
Keywords: immune system cancer antibiotics antibiotic resistance preclinical translational research non-linear mixed effects modelling pharmacokinetics pharmacometrics pharmacodynamics translational medicine modeling and simulation anticancer therapy bacterial infections drug development drug usage vaccines
Lena is since 2021 employed as Professor of Pharmacokinetics and Pharmacodynamics (Professor of Pharmacometrics 2014-2021). She obtained her PhD in 2003 and in 2007 she became Docent (Associate professor). During 2003-2008 she was supported by a personal grant from Knut & Alice Wallenberg foundation for a postdoc at the University of Queensland, Australia, and as a researcher at Uppsala University.
The research focuses on developing approaches for predictive translation of effects from preclinical data to patients, both for desired outcomes and adverse events. Important achievements include frameworks to be applied for optimized dosing strategies of new and available drugs in the areas of oncology and infection.
Lena has published >160 peer-reviewed research articles and has an h-index of 51. She has been main (co) supervisor of 12 (10) students to PhD degree and is currently supervising 8 (2) PhD students, in addition to mentoring Postdocs and early researchers. She holds competitive grants from Swedish Research Council, Swedish Cancer Society, Swedish Childhood Cancer Fund, Innovative Medicines Initiative (EU-IMI2) and Marie Skłodowska-Curie Innovative Training Networks (ITN). Lena has received the Giorgio Segré Prize from EUFEPS for “distinct research in the Pharmacokinetic-Pharmacodynamic area”, the Innovation award from ISoP and been appointed ISoP fellow and Key Scientist" by Vinnova/BioSweden. She is the deputy Editor-in-chief of the journal CPT: Pharmacometrics & Systems Pharmacology.
Dr Friberg is also heading the teaching unit Pharmacokinetics, Pharmacotherapy and Clinical Pharmacy. In addition to teaching undergraduate students in PKPD, Pharmacometrics and Drug development, she also gives courses to professionals on PKPD-modeling and the use of translation for improved drug development.
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