Margareta Hammarlund-Udenaes

Professor emeritus at Department of Pharmacy, Translational PKPD

Email:
margareta.hammarlund-udenaes[AT-sign]farmaci.uu.se
Mobile phone:
+46 70 4250485
Visiting address:
Biomedicinskt Centrum BMC, Husargatan 3
752 37 Uppsala
Postal address:
Box 580
751 23 UPPSALA

Professor at Department of Pharmacy, Translational PKPD

Email:
margareta.hammarlund-udenaes[AT-sign]farmbio.uu.se
Telephone:
+4618-471 4300
Mobile phone:
+46 70 4250485
Visiting address:
Room BMC B3:4 Biomedicinskt Centrum BMC, Husargatan 3
752 37 Uppsala
Postal address:
Box 580
751 23 UPPSALA

This paragraph is not available in English, therefore the Swedish version is shown.

Within the area of translational PKPD we address conversion of pharmacokinetic data from the preclinical to the clinical setting. This is strongly needed for optimizing drug discovery processes and promoting efficient treatment of CNS diseases.

We are interested in brain drug delivery in relation to transport processes of both small and large molecules across the blood brain barrier (BBB), where a quantitative role of nanocarriers is specifically studied.

Using the concepts and methodologies developed for the brain we are also exploring drug distribution in the lung. This is important for the design and evaluation of lung targeted drugs which may be administered by inhalation.

For this purpose, methods are being developed to help analyzing the pharmacologically relevant unbound concentrations in brain and other tissues.

Our work also emphasizes the importance of bridging the expertise within academia and pharmaceutical industry in order to seek excellence in method development for better therapeutics treating CNS and lung disorders.

Read more at https://farmaci.uu.se/research/translational-pkpd/methodological-research/

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Margareta Hammarlund-Udenaes