Dominic-Luc Webb

Short presentation

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Publications

Recent publications

• High iNOS and IL-1β immunoreactivity are features of colitis-associated colorectal cancer tumors, but fail to predict 5-year survival (2023)
• Acyl ghrelin increases cardiac output while preserving right ventricular-pulmonary arterial coupling in heart failure (2023)
• Trophozoite fitness dictates the intestinal epithelial cell response to Giardia intestinalis infection (2023)
• Acyl ghrelin infusion increases circulating growth hormone in patients with heart failure and reduced ejection fraction (2023)
• Acyl ghrelin improves cardiac function in heart failure and increases fractional shortening in cardiomyocytes without calcium mobilization (2023)

All publications

Articles

• High iNOS and IL-1β immunoreactivity are features of colitis-associated colorectal cancer tumors, but fail to predict 5-year survival (2023)
• Acyl ghrelin increases cardiac output while preserving right ventricular-pulmonary arterial coupling in heart failure (2023)
• Trophozoite fitness dictates the intestinal epithelial cell response to Giardia intestinalis infection (2023)
• Acyl ghrelin infusion increases circulating growth hormone in patients with heart failure and reduced ejection fraction (2023)
• Acyl ghrelin improves cardiac function in heart failure and increases fractional shortening in cardiomyocytes without calcium mobilization (2023)
• Haptoglobin in Juvenile Idiopathic Arthritis (2022)
• Impact of biliopancreatic diversion with duodenal switch on glucose homeostasis and gut hormones and their correlations with appetite (2022)
• Intra- and inter-subject variability in gastric pH following a low-fat, low-calorie meal (2022)
• Infliximab Peak and 1-Week Serum Level Estimates Predict 8-Week Trough Levels in Inflammatory Bowel Disease (2022)
• Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat (2022)
• Pain relief and pain intensity response to GLP-1 receptor agonist ROSE-010 in irritable bowel syndrome (2022)
• Limited value of neutrophil-to-lymphocyte ratio and serum creatinine as point-of-care biomarkers of disease severity and infection mortality in patients hospitalized with COVID-19 (2022)
• Inflammatory mediators profile in patients hospitalized with COVID-19 (2022)
• Correlation Between Gastric Emptying Patterns, Hunger And Satiety as Regulated by Ghrelin and Glucagon-Like Peptide-1 (2022)
• High-Definition DIC Imaging Uncovers Transient Stages of Pathogen Infection Cycles on the Surface of Human Adult Stem Cell-Derived Intestinal Epithelium (2022)
• Gastrointestinal Physiology Before and After Duodenal Switch with Comparisons to Unoperated Lean Controls (2021)
• Salmonella enterica Serovar Typhimurium Exploits Cycling through Epithelial Cells To Colonize Human and Murine Enteroids (2021)
• Elevated gaseous luminal nitric oxide and circulating IL-8 as features of Helicobacter pylori-induced gastric inflammation (2021)
• Receptor-Mediated Response to Peptide Yy(1-36) and Peptide Yy(3-36) in Reductiono of Sensitivity to Rectal Distension in Patients With Irritable Bowel Syndrome (2021)
• Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers (2021)
• Concurrent Derangements in Transit Times and Meal Responses of Ghrelin, Motilin and Glp-1 in Myogenic and Neurogenic Chronic Intestinal Pseudo-Obstruction (2021)
• Inflammatory Status of Post-Infectious Irritable Bowel Syndrome Patients Before and After Fecal Microbiota Transplantation (2020)
• Non-responders After Gastric Bypass Surgery for Morbid Obesity (2019)
• Tests of intestinal mucosal hyperpermeability (2019)
• Small intestinal lactulose and sucralose hyper-permeability in inflammatory bowel disease (2018)
• Glucagon-like peptide-1 inhibits prandial gastrointestinal motility through myenteric neuronal mechanisms in humans (2018)
• Parallel Changes in Harvey-Bradshaw Index, TNFα, and Intestinal Fatty Acid Binding Protein  in Response to Infliximab in Crohn’s Disease (2017)
• Validation of SmartPill® wireless motility capsule for gastrointestinaltransit time (2017)
• The Role of Episodic Postprandial Peptides in Exercise-Induced Compensatory Eating (2017)
• Intestinal fatty acid binding protein parallels temporal changes in Harvey-Bradshaw Index and TNF alpha in response to infliximab in Crohn’s disease (2017)
• Slow-release L-cysteine capsule prevents gastric mucosa exposure to carcinogenic acetaldehyde (2017)
• Boronic acid recognition of non-interacting carbohydrates for biomedical applications (2017)
• Bariatric surgery - time to replace with GLP-1? (2017)
• Postprandial profiles of CCK after high fat and high carbohydrate meals and the relationship to satiety in humans (2016)
• GLP-1 Inhibits Prandial Antro-Duodeno-Jejunal Motility in Humans: Native GLP-1 Compared With Analogue ROSE-010 In Vitro (2016)
• Effects of whole-grain rye porridge with added inulin and wheat gluten on appetite, gut fermentation and postprandial glucose metabolism (2016)
• Multiwell Assay for the Analysis of Sugar Gut Permeability Markers (2016)
• Visually induced nausea causes characteristic changes in cerebral, autonomic and endocrine function in humans (2015)
• Nitric oxide regulation of migrating motor complex (2015)
• Nitric oxide regulation of migrating motor complex (2015)
• Luminal Nitric Oxide and Plasma Nitrite/Nitrate As Predictors of Colectomy in Corticosteroid-Treated Acute Colitis (2015)
• Rapid small intestinal permeability assay based on riboflavin and lactulose detected by bis-boronic acid appended benzyl viologens (2015)
• Neuropeptide S Reduces Gut Motility in Rats and Humans (2015)
• Neuropeptide S inhibits gastrointestinal motility and increases mucosal permeability through nitric oxide (2015)
• Fasting Leptin Is a Metabolic Determinant of Food Reward in Overweight and Obese Individuals during Chronic Aerobic Exercise Training (2014)
• Neuropeptide S reduce small intestinal motility in rats and humans (2014)
• Intravenous ghrelin accelerates postoperative gastric emptying and time to first bowel movement in humans (2013)
• Gastrointestinal Peptide Response To Fat And Carbohydrate (2013)
• Susceptibility And Resistance To Exercise-induced Weight Loss Mediated By Physiological And Psychological Components Of Appetite (2013)
• Comparison of Postprandial Profiles of Ghrelin, Active GLP-1, and Total PYY to Meals Varying in Fat and Carbohydrate and Their Association With Hunger and the Phases of Satiety (2013)
• The type 2 CCK/gastrin receptor antagonist YF476 acutely prevents NSAID-induced gastric ulceration while increasing iNOS expression (2013)
• Whole grain rye breakfast (2012)
• Irritable Bowel syndrome (2011)
• Tissue-dependent loss of phosphofructokinase-M in mice with interrupted activity of the distal promoter (2007)
• Neuronal calcium sensor-1 potentiates glucose-dependent exocytosis in pancreatic beta cells through activation of phosphatidylinositol 4-kinase beta (2005)
• Glutamate inhibits protein phosphatases and promotes insulin exocytosis in pancreatic beta-cells (2005)
• Dihydroxyacetone-induced oscillations in cytoplasmic free Ca2+ and the ATP/ADP ratio in pancreatic beta-cells at substimulatory glucose. (2003)
• Cyclin-dependent kinase 5 promotes insulin exocytosis (2001)
• Insulin exocytosis and glucose-mediated increase in cytoplasmic free Ca2+ concentration in the pancreatic beta-cell are independent of cyclic ADP-ribose (1996)
• Two separate plasma membrane Ca2+ carriers participate in receptor-mediated Ca2+ influx in rat hepatocytes. (1994)
• Receptor-mediated Mn2+ influx in rat hepatocytes (1994)
• Gastrointestinal motility examined by wireless motility capsule (SmartPill^®) and gut hormone profiles in inflammatory bowel diseases
• Concurrent small and large intestinal permeability in inflammatory bowel disease
• Glucagon-like peptide-1 inhibits prandial gastrointestinal motility through myenteric neuronal mechanisms in humans

Conferences

• Non-Responders After Gastric Bypass (2017)
• Non-Responders after Gastric Bypass Surgery for Morbid Obesity (2017)