Fredrik Jernerén
Senior Lecturer/Associate Professor at Institutionen för farmaceutisk biovetenskap; Forskning; Neurofarmakologi och biologisk beroendeforskning
- Telephone:
- +46 18 471 42 24
- Mobile phone:
- +46 72 999 93 14
- E-mail:
- fredrik.jerneren@uu.se
- Visiting address:
- Biomedicinskt centrum BMC, Husargatan 3
- Postal address:
- Box 591
751 24 UPPSALA
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Short presentation
Associate Professor, Ph.D, M. Sc. Pharm., licensed pharmacist
Biography
2005: Master of Pharmacy, licensed pharmacist
2011: Ph.D in Biochemical Pharmacology
2012-2015: Post.doc, University of Oxford, Dept. of Pharmacology
2018: Associate professor (docent) in Pharmacology
Publications
Selection of publications
- Homocysteine Status Modifies the Treatment Effect of Omega-3 Fatty Acids on Cognition in a Randomized Clinical Trial in Mild to Moderate Alzheimer's Disease (2019)
- Homocysteine concentrations in the cognitive progression of Alzheimer's disease (2017)
- A new class of fatty acid allene oxide formed by the DOX-P450 fusion proteins of human and plant pathogenic fungi, C. immitis and Z. tritici. (2016)
- Omega-3 Fatty Acid Status Enhances the Prevention of Cognitive Decline by B Vitamins in Mild Cognitive Impairment. (2016)
- Brain atrophy in cognitively impaired elderly (2015)
- Post-sampling release of free fatty acids - (2015)
- Linolenate 9R-Dioxygenase and Allene Oxide Synthase Activities of Lasiodiplodia theobromae (2012)
- The Fatty Acid 8,11-Diol Synthase of Aspergillus fumigatus is Inhibited by Imidazole Derivatives and Unrelated to PpoB (2012)
- Reaction mechanism of 5,8-linoleate diol synthase, 10R-dioxygenase, and 8,11-hydroperoxide isomerase of Aspergillus clavatus (2010)
- Linoleate 9R-dioxygenase and allene oxide synthase activities of Aspergillus terreus (2010)
- Gene deletion of 7,8-linoleate diol synthase of the rice blast fungus (2010)
Recent publications
- Changes in plasma fatty acids and related biomarkers during transition to an exclusively plant- and fish-based diet in healthy adults (2021)
- Extracellular cystine influences human preadipocyte differentiation and correlates with fat mass in healthy adults (2021)
- Pesticide-induced multigenerational effects on amphibian reproduction and metabolism (2021)
- ω-3 fatty acids and their interactions (2021)
- Effects of Peroral Omega-3 Fatty Acid Supplementation on Cerebrospinal Fluid Biomarkers in Patients with Alzheimer's Disease (2021)
All publications
Articles
- Changes in plasma fatty acids and related biomarkers during transition to an exclusively plant- and fish-based diet in healthy adults (2021)
- Extracellular cystine influences human preadipocyte differentiation and correlates with fat mass in healthy adults (2021)
- Pesticide-induced multigenerational effects on amphibian reproduction and metabolism (2021)
- ω-3 fatty acids and their interactions (2021)
- Effects of Peroral Omega-3 Fatty Acid Supplementation on Cerebrospinal Fluid Biomarkers in Patients with Alzheimer's Disease (2021)
- Exhaustive Exercise and Post-exercise Protein Plus Carbohydrate Supplementation Affect Plasma and Urine Concentrations of Sulfur Amino Acids, the Ratio of Methionine to Homocysteine and Glutathione in Elite Male Cyclists (2020)
- Homocysteine Status Modifies the Treatment Effect of Omega-3 Fatty Acids on Cognition in a Randomized Clinical Trial in Mild to Moderate Alzheimer's Disease (2019)
- Food Overconsumption in Healthy Adults Triggers Early and Sustained Increases in Serum Branched-Chain Amino Acids and Changes in Cysteine Linked to Fat Gain (2018)
- Perfluorooctanoic acid (PFOA) exposure promotes proliferation, migration and invasion potential in human breast epithelial cells (2018)
- Protein intake in the early recovery period after exhaustive exercise improves performance the following day. (2018)
- Purification and site-directed mutagenesis of linoleate 9S-dioxygenase-allene oxide synthase of Fusarium oxysporum confirms the oxygenation mechanism (2017)
- Amino acid changes during transition to a vegan diet supplemented with fish in healthy humans. (2017)
- Homocysteine concentrations in the cognitive progression of Alzheimer's disease (2017)
- Cysteine deprivation prevents induction of peroxisome proliferator-activated receptor gamma-2 and adipose differentiation of 3T3-L1 cells. (2017)
- The Choice of Euthanasia Method Affects Metabolic Serum Biomarkers (2017)
- Serum S-adenosylmethionine, but not methionine, increases in response to overfeeding in humans. (2016)
- Exploring the Lean Phenotype of Glutathione-Depleted Mice (2016)
- A new class of fatty acid allene oxide formed by the DOX-P450 fusion proteins of human and plant pathogenic fungi, C. immitis and Z. tritici. (2016)
- Omega-3 Fatty Acid Status Enhances the Prevention of Cognitive Decline by B Vitamins in Mild Cognitive Impairment. (2016)
- Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels. (2016)
- Brain atrophy in cognitively impaired elderly (2015)
- Post-sampling release of free fatty acids - (2015)
- Expression and characterization of manganese lipoxygenase of the rice blast fungus reveals prominent sequential lipoxygenation of α-linolenic acid (2015)
- Epoxy alcohol synthase of the rice blast fungus represents a novel subfamily of dioxygenase-cytochrome P450 fusion enzymes (2014)
- Expression of Fusion Proteins of Aspergillus terreus Reveals a Novel Allene Oxide Synthase (2013)
- Linolenate 9R-Dioxygenase and Allene Oxide Synthase Activities of Lasiodiplodia theobromae (2012)
- The Fatty Acid 8,11-Diol Synthase of Aspergillus fumigatus is Inhibited by Imidazole Derivatives and Unrelated to PpoB (2012)
- Catalytic convergence of manganese and iron lipoxygenases by replacement of a single amino Acid (2012)
- Expression of 5,8-LDS of Aspergillus fumigatus and its dioxygenase domain (2011)
- Manganese lipoxygenase oxidizes bis-allylic hydroperoxides and octadecenoic acids by different mechanisms (2011)
- Stereoselective oxidation of regioisomeric octadecenoic acids by fatty acid dioxygenases (2011)
- Reaction mechanism of 5,8-linoleate diol synthase, 10R-dioxygenase, and 8,11-hydroperoxide isomerase of Aspergillus clavatus (2010)
- Linoleate 9R-dioxygenase and allene oxide synthase activities of Aspergillus terreus (2010)
- Gene deletion of 7,8-linoleate diol synthase of the rice blast fungus (2010)
- Identification of dioxygenases required for Aspergillus development (2007)
Books
