Senior Lecturer/Associate Professor at Department of Cell and Molecular Biology, Structural Biology
- Visiting address:
- Husargatan 3
752 37 Uppsala
- Postal address:
- Box 596
Keywords: neurodegeneration structural biology cryo-electron microscopy membrane remodeling bar proteins mitochondrial dynamics membrane biophysics
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Dr. Anna Sundborger-Lunna received a M.Sc degree in Medical Biology from Linköping University in 2005 and a PhD in Neuroscience from Karolinska Institutet in 2010. She joined the laboratory of Dr. Jenny Hinshaw at the National Institutes of Health in 2010 to study the mechanisms of dynamin-mediated membrane fission using cryo-EM and various biochemical and biophysical methods. Dr. Sundborger-Lunna was recruited to the University of Minnesota Hormel Institute in 2016 to establish a new state-of-the-art cryo-EM facility and joined the Uppsala University ICM faculty in 2021 to establish a new cryo-EM facility and to continue her work on elucidating structure-function of membrane remodelling proteins and their roles in mitochondrial dynamics and cellular degeneration.
Dr. Sundborger-Lunna's research focuses on unraveling the molecular mechanisms underlying membrane remodeling and cell death using a multi-disciplinary approach combining cryo-EM and complementary structural biology methods, biochemical/cell-free assays, and cell-based functional models and aims to answer an outstanding question in cell biology; How is the critical process of mitochondrial dynamics regulated and coordinated during neuronal cell death/survival signaling? The long-term objective of providing novel targets for therapeutic strategies to prevent neurodegeneration and to treat debilitating diseases like Parkinson’s and Huntingtin’s diseases.
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