My research focuses on how endocrine disrupting chemicals, i.e. chemicals that interfere with our endogenous hormone system, affect neurodevelopment. I engage in multidisciplinary projects to address the full complexity of this topic, coupling molecular mechanisms to human health, and translating scientific insights into regulatory and political decisions. I am coordinator of one such project, the Horizon 2020-funded ENDpoiNTs. Read more about my research here.
Keywords: epigenetics blood brain barrier neurodevelopmental disorders endocrine disruptors molecular toxicology chemical mixtures
Diploma in Biochemistry, University of Zürich (1994-1999)
MSc in Neuroscience, University of Edinburgh (1999-2000)
PhD Ludwig Maximilian University München, (2000-2004)
Docent in Toxicology, Karolinska Institutet 2018Professor in Environmental Toxicology, Uppsala University 2019
My research focusses on the question how early life exposure to endocrine disrupting chemicals (EDCs) affects human (neuro)development via epigenetic changes, i.e. long-lasting changes in gene regulation that do not involve alteration in the DNA sequence. In the Molecular Toxicology and Epigenetics group, we are working on four main projects:
- ENDpoiNTs, a H2020-funded research and innovation action including 16 participants, that aims at developing novel testing methods and strategies to identify chemicals that affect neurodevelopment via endocrine disrupting mechanisms.
- RACH-Mix, a Formas-funded project where we identify epigenetic changes induced by chemical mixtures and address their value as early markers for human exposure-linked disease risk.
- The Formas-funded BBB project, in which we investigate the effect of EDCs on the human blood-brain barrier using advanced in vitro models, and link our results to epidemiological findings.
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