Gerrit Brandis
Associate senior lecturer/Assistant Professor at Institutionen för cell- och molekylärbiologi; Molekylär systembiologi
- E-mail:
- gerrit.brandis@icm.uu.se
- Visiting address:
- Husargatan 3
752 37 UPPSALA - Postal address:
- Box 596
751 24 UPPSALA
Associate senior lecturer/Assistant Professor at Institutionen för cell- och molekylärbiologi; Molekylärbiologi
- Visiting address:
- Husargatan 3
752 37 Uppsala - Postal address:
- Box 596
751 24 Uppsala
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Keywords
- antibiotic resistance
- bacterial genetics
- chromosomal organization
- experimental evolution
Publications
Selection of publications
- Mutation supply and relative fitness shape the genotypes of ciprofloxacin-resistant Escherichia coli (2017)
- Autoregulation of the tufB operon in Salmonella (2016)
- The Selective Advantage of Synonymous Codon Usage Bias in Salmonella (2016)
- Comprehensive phenotypic characterization of rifampicin resistance mutations in Salmonella provides insight into the evolution of resistance in Mycobacterium tuberculosis (2015)
Recent publications
- Antibiotic perseverance increases the risk of resistance development (2023)
- Evolution of Bacterial Interspecies Hybrids with Enlarged Chromosomes (2022)
- Positive Selection during Niche Adaptation Results in Large-Scale and Irreversible Rearrangement of Chromosomal Gene Order in Bacteria (2022)
- Genetic Architecture and Fitness of Bacterial Interspecies Hybrids (2021)
- Reconstructing the Evolutionary History of a Highly Conserved Operon Cluster in Gammaproteobacteria and Bacilli (2021)
All publications
Articles
- Antibiotic perseverance increases the risk of resistance development (2023)
- Evolution of Bacterial Interspecies Hybrids with Enlarged Chromosomes (2022)
- Positive Selection during Niche Adaptation Results in Large-Scale and Irreversible Rearrangement of Chromosomal Gene Order in Bacteria (2022)
- Genetic Architecture and Fitness of Bacterial Interspecies Hybrids (2021)
- Reconstructing the Evolutionary History of a Highly Conserved Operon Cluster in Gammaproteobacteria and Bacilli (2021)
- Expression of the qepA1 gene is induced under antibiotic exposure (2021)
- Mutant RNA polymerase can reduce susceptibility to antibiotics via ppGpp-independent induction of a stringent-like response (2021)
- Chromosomal Location Determines the Rate of Intrachromosomal Homologous Recombination in Salmonella (2021)
- Resistance/fitness trade-off is a barrier to the evolution of MarR inactivation mutants in Escherichia coli (2021)
- The SNAP hypothesis (2020)
- Population Bottlenecks Strongly Influence the Evolutionary Trajectory to Fluoroquinolone Resistance in Escherichia coli (2020)
- Antibiotic resistance by high-level intrinsic suppression of a frameshift mutation in an essential gene (2020)
- Operon Concatenation Is an Ancient Feature That Restricts the Potential to Rearrange Bacterial Chromosomes (2019)
- Measuring Homologous Recombination Rates between Chromosomal Locations in Salmonella (2019)
- Co-evolution with recombination affects the stability of mobile genetic element insertions within gene families of Salmonella (2018)
- Mechanisms of fitness cost reduction for rifampicin-resistant strains with deletion or duplication mutations in rpoB. (2018)
- Transcriptional Regulation Buffers Gene Dosage Effects on a Highly Expressed Operon in Salmonella (2018)
- Having your cake and eating it - Staphylococcus aureus small colony variants can evolve faster growth rate without losing their antibiotic resistance (2017)
- Alternative Evolutionary Pathways for Drug-Resistant Small Colony Variant Mutants in Staphylococcus aureus (2017)
- Mutation supply and relative fitness shape the genotypes of ciprofloxacin-resistant Escherichia coli (2017)
- Ciprofloxacin selects for RNA polymerase mutations with pleiotropic antibiotic resistance effects (2017)
- Fitness cost constrains the spectrum of marR mutations in ciprofloxacin-resistant Escherichia coli (2017)
- Autoregulation of the tufB operon in Salmonella (2016)
- The Selective Advantage of Synonymous Codon Usage Bias in Salmonella (2016)
- Evidence for the critical role of a secondary site rpoB mutation in the compensatory evolution and successful transmission of an MDR tuberculosis outbreak strain (2016)
- Comprehensive phenotypic characterization of rifampicin resistance mutations in Salmonella provides insight into the evolution of resistance in Mycobacterium tuberculosis (2015)
- Genetic characterization of compensatory evolution in strains carrying rpoB Ser531Leu, the rifampicin resistance mutation most frequently found in clinical isolates (2013)
- Rifampicin Resistance (2013)
- Fitness-compensatory mutations in rifampicin-resistant RNA polymerase (2012)
- IncP-1β plasmids of Comamonas sp. and Delftia sp. strains isolated from a wastewater treatment plant mediate resistance to and decolorization of the triphenylmethane dye crystal violet (2012)
Books
