Daniel Globisch
Professor vid Institutionen för kemi - BMC; Analytisk kemi; Globisch grupp
- Telefon:
- 070-425 01 39, 018-471 36 30
- E-post:
- daniel.globisch@kemi.uu.se
- Besöksadress:
- Husargatan 3 (D5)
752 37 Uppsala - Postadress:
- Box 599
75124 Uppsala
Mer information visas för dig som medarbetare om du loggar in.
Kort presentation
Associate Professor and SciLifeLab Fellow with focus on Biomarker Discovery using techniques at the interface of Chemistry and Biology including Chemical Biology, Organic Chemistry, mass spectrometry-based investigation of human samples, and metabolomics-methodologies.
My details can be found at:
Nyckelord
- biomarker discovery
- bioorganic chemistry
- chemical biology
- gut microbiota
- mass spectrometry
- metabolomics
- microbiome
- organic chemistry
Biografi
- 12/20 – present Uppsala University, Sweden; Associate Professor (tenured)
- 04/17 – 12/20 Uppsala University, Sweden; Associate Professor
- 08/15 – 04/17 Uppsala University, Sweden; Assistant Professor
- 04/11 – 08/15 The Scripps Research Institute, La Jolla, USA; PostDoc with Professor Kim D. Janda, Ph.D.
- 03/07 – 03/11 Ludwig-Maximilians-University Munich, Germany; PhD student with Professor Dr. Thomas Carell
- 04/06 – 01/07 & 04/05 – 07/05 University of Southern Denmark
- 10/01 – 03/06 Technical University Kaiserslautern, Germany
Publikationer
Urval av publikationer
- Chemoselective bicyclobutane-based mass spectrometric detection of biological thiols uncovers human and bacterial metabolites (2023)
- Identification of nutritional biomarkers through highly sensitive and chemoselective metabolomics (2023)
- Immobilized Enzymes on Magnetic Beads for Separate Mass Spectrometric Investigation of Human Phase II Metabolite Classes (2023)
- Chemoselective and Highly Sensitive Quantification of Gut Microbiome and Human Metabolites (2021)
- Unexpected Acetylation of Endogenous Aliphatic Amines by ArylamineN-Acetyltransferase NAT2 (2020)
- Sensitive mass spectrometric analysis of carbonyl metabolites in human urine and fecal samples using chemoselective modification (2020)
- DNA surface exploration and operator bypassing during target search (2020)
- Chemoselective probe for detailed analysis of ketones and aldehydes produced by gut microbiota in human samples (2019)
- New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites (2018)
- Chemoselective Probe Containing a Unique Bioorthogonal Cleavage Site for Investigation of Gut Microbiota Metabolism (2018)
- Noninvasive Urine Biomarker Lateral Flow Immunoassay for Monitoring Active Onchocerciasis (2018)
Senaste publikationer
- Rapid and Bifunctional Chemoselective Metabolome Analysis of Liver Disease Plasma Using the Reagent 4‐Nitrophenyl‐2H‐azirine (2024)
- A frame-shift mutation in COMTD1 is associated with impaired pheomelanin pigmentation in chicken (2023)
- Chemoselective bicyclobutane-based mass spectrometric detection of biological thiols uncovers human and bacterial metabolites (2023)
- Sensitive quantification of short-chain fatty acids combined with global metabolomics in microbiome cultures (2023)
- Identification of nutritional biomarkers through highly sensitive and chemoselective metabolomics (2023)
Alla publikationer
Artiklar
- Rapid and Bifunctional Chemoselective Metabolome Analysis of Liver Disease Plasma Using the Reagent 4‐Nitrophenyl‐2H‐azirine (2024)
- A frame-shift mutation in COMTD1 is associated with impaired pheomelanin pigmentation in chicken (2023)
- Chemoselective bicyclobutane-based mass spectrometric detection of biological thiols uncovers human and bacterial metabolites (2023)
- Sensitive quantification of short-chain fatty acids combined with global metabolomics in microbiome cultures (2023)
- Identification of nutritional biomarkers through highly sensitive and chemoselective metabolomics (2023)
- Mucosal and Plasma Metabolomes in New-onset Paediatric Inflammatory Bowel Disease (2023)
- Immobilized Enzymes on Magnetic Beads for Separate Mass Spectrometric Investigation of Human Phase II Metabolite Classes (2023)
- Analysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors (2022)
- Regional Brain Analysis of Modified Amino Acids and Dipeptides during the Sleep/Wake Cycle (2022)
- Enhanced cytotoxicity of a novel family of ATPase inhibitors in colorectal cancer cells with high NAT2 activity (2022)
- Investigation of the individual human sulfatome in plasma and urine samples reveals an age-dependency (2021)
- Comparison of two arylsulfatases for targeted mass spectrometric analysis of microbiota-derived metabolites (2021)
- Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis (2021)
- Chemoselective and Highly Sensitive Quantification of Gut Microbiome and Human Metabolites (2021)
- Squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines (2021)
- Differential regulation of oxidative stress, microbiota-derived, and energy metabolites in the mouse brain during sleep (2021)
- Unexpected Acetylation of Endogenous Aliphatic Amines by ArylamineN-Acetyltransferase NAT2 (2020)
- Unexpected Acetylation of Endogenous Aliphatic Amines by Arylamine N-Acetyltransferase NAT2. (2020)
- Comparative dietary sulfated metabolome analysis reveals unknown metabolic interactions of the gut microbiome and the human host (2020)
- Rapid Preparation of a Large Sulfated Metabolite Library for Structure Validation in Human Samples (2020)
- Sensitive mass spectrometric analysis of carbonyl metabolites in human urine and fecal samples using chemoselective modification (2020)
- DNA surface exploration and operator bypassing during target search (2020)
- Amino Acid Modified RNA Bases as Building Blocks of an Early Earth RNA-Peptide World (2020)
- Chemoselective probe for detailed analysis of ketones and aldehydes produced by gut microbiota in human samples (2019)
- Coupled Enzymatic Treatment and Mass Spectrometric Analysis for Identification of Glucuronidated Metabolites in Human Samples (2019)
- Comprehensive kinetic and substrate specificity analysis of an arylsulfatase from Helix pomatia using mass spectrometry (2019)
- New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites (2018)
- Chemoselective Probe Containing a Unique Bioorthogonal Cleavage Site for Investigation of Gut Microbiota Metabolism (2018)
- Structural elucidation of major selective androgen receptor modulator (SARM) metabolites for doping control (2018)
- Noninvasive Urine Biomarker Lateral Flow Immunoassay for Monitoring Active Onchocerciasis (2018)
- Validation of onchocerciasis biomarker N-acetyltyramine-O-glucuronide (NATOG) (2017)
