Peter Frykholm
Adjungerad universitetslektor vid Institutionen för kirurgiska vetenskaper; Anestesiologi och intensivvård
- Telefon:
- 072-239 73 47
- Mobiltelefon:
- 070-845 49 69
- E-post:
- peter.frykholm@uu.se
- Besöksadress:
- Akademiska sjukhuset, ingång 70, 1tr
751 85 Uppsala - Postadress:
- Akademiska sjukhuset, ingång 70, 1tr
751 85 UPPSALA
- Akademiska meriter:
- MD, PhD, Docent i anestesiologi och intensivvård
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Biografi
Peter Frykholm tog läkarexamen 1991 vid Uppsala Universitet, gjorde sedan sin allmäntjänstgöring och specialistutbildning inom anestesi- och intensivvård på Länssjukhuset Gävle-Sandviken. Han disputerade 2002 på en avhandling med titeln Cerebral Ischemia Studied with PET and Microdialysis, efter doktorandutbildning på Uppsala Universitet med Per Enblad som huvudhandledare. Docentur tilldelades 2013.
Som anestesiolog har Peter Frykholm subspecialiserat sig inom barnanestesi- och intensivvård, bl a genom ett kliniskt fellowship vid barnintensivvårdsavdelningen i Auckland, Nya Zeeland. Har har även engagerat sig inom områdena respiration, intravenös access och svår luftväg, inom SFAI och lokalt.
Peter har ett brett forskningintresse med klinisk förankring. Aktuella områden är metoder för monitorering och optimering av lungfunktion och ventilation under anestesi och intensivvård, fysiologi, farmakologi och farmakodynamik inom barnanestesi, betydelsen av fasta inför barnanestesi samt immobilisering av lungor vid diagnostik och behandling.
Publikationer
Urval av publikationer
- Influence of Tracheal Obstruction on the Efficacy of Superimposed High-frequency Jet Ventilation and Single-frequency Jet Ventilation (2015)
- Clinical guidelines on central venous catheterisation (2014)
- Efficacy of Superimposed High Frequency Jet Ventilation and High Frequency Jet Ventilation in an Animal Model of Tracheal Obstruction (2014)
- Frequency dependence of lung volume changes during superimposed high-frequency jet ventilation and high-frequency jet ventilation (2014)
- Comparison of superimposed high-frequency jet ventilation with conventional jet ventilation for laryngeal surgery (2012)
- Early Release of Interalveolar Synechiae Under General Anesthesia Through Fiberscopic Nasal Intubation (2012)
- Optimizing positive end-expiratory pressure by oscillatory mechanics minimizes tidal recruitment and distension (2012)
- Positive end-expiratory pressure optimization with forced oscillation technique reduces ventilator induced lung injury (2011)
Senaste publikationer
- Clear rules for clear fluids fasting in children (2024)
- Randomized cross-over study investigating the tolerability and side effects of an intra-oral air-cooling device compared to ice in healthy volunteers (2023)
- Ephedrine to treat intraoperative hypotension in infants (2023)
- Reply to (2023)
- The Aura-Gain laryngeal mask for airway management in neonatal inguinal hernia surgery (2023)
Alla publikationer
Artiklar
- Clear rules for clear fluids fasting in children (2024)
- Randomized cross-over study investigating the tolerability and side effects of an intra-oral air-cooling device compared to ice in healthy volunteers (2023)
- Ephedrine to treat intraoperative hypotension in infants (2023)
- Reply to (2023)
- The Aura-Gain laryngeal mask for airway management in neonatal inguinal hernia surgery (2023)
- Pre-operative fasting in children (2022)
- The rationale for the recommendations of the European Paediatric Fasting Guideline (2022)
- Harmonising paediatric anaesthesia training in Europe (2022)
- Effect of high-flow nasal oxygen on postoperative oxygenation in obese patients (2022)
- Perioperative fasting times in children and adolescents (2022)
- Pro-Con Debate (2021)
- Physiological changes and compensatory mechanisms by the action of respiratory muscles in a porcine model of phrenic nerve injury (2021)
- The COVID-19 pandemic first wave in Sweden (2021)
- High-flow nasal cannula versus face mask for preoxygenation in obese patients (2021)
- Letter to the Editor in response to "Find the real responders and improve the outcome of awake prone positioning" (2021)
- Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19 (2021)
- Role of Renal Sympathetic Nerve Activity in Volatile Anesthesia's Effect on Renal Excretory Function (2021)
- Visual aids for pediatric airway management (2020)
- Comparison of different methods for lung immobilization in an animal model (2020)
- The impaired diaphragmatic function after bilateral lung transplantation (2020)
- Report from the First International Meeting on Iterative Pediatric Anesthesia (2020)
- Reply to 'Testing mask ventilation: It's capnography that counts' (2020)
- Gastric content assessed with gastric ultrasound in paediatric patients prescribed a light breakfast prior to general anaesthesia (2019)
- Adaptation of lung, chest wall, and respiratory muscles during pregnancy (2019)
- Checking mask ventilation before neuromuscular block (2019)
- Introducing the 6-4-0 fasting regimen and the incidence of prolonged preoperative fasting in children (2018)
- Preoperative fasting guidelines in pediatric anesthesia (2018)
- Preoperative fasting in children (2018)
- Specific anesthesia-induced lung volume changes from induction to emergence (2018)
- The Effect Of Pregnancy On Respiratory Function (2018)
- The diaphragm before and after lung transplant (LT) (2018)
- The ventilatory pattern and the operational volumes during exercise in subjects with diagnosed exercise-induced laryngeal obstruction (EILO) (2018)
- An evaluation of the mixed pediatric unit for blood loss replacement in pediatric craniofacial surgery (2017)
- Fourth Swedish difficult airway guidelines (2017)
- Vascular access (2016)
- Low incidence of pulmonary aspiration in children allowed intake of clear fluids until called to the operating suite (2015)
- Influence of Tracheal Obstruction on the Efficacy of Superimposed High-frequency Jet Ventilation and Single-frequency Jet Ventilation (2015)
- Influence of Tracheal Obstruction on the Efficacy of Superimposed High-frequency Jet Ventilation and Single-frequency Jet Ventilation (2015)
- Clinical guidelines on central venous catheterisation (2014)
- Efficacy of Superimposed High Frequency Jet Ventilation and High Frequency Jet Ventilation in an Animal Model of Tracheal Obstruction (2014)
- Frequency dependence of lung volume changes during superimposed high-frequency jet ventilation and high-frequency jet ventilation (2014)
- Comparison of superimposed high-frequency jet ventilation with conventional jet ventilation for laryngeal surgery (2012)
- Early Release of Interalveolar Synechiae Under General Anesthesia Through Fiberscopic Nasal Intubation (2012)
- Optimizing positive end-expiratory pressure by oscillatory mechanics minimizes tidal recruitment and distension (2012)
- Effects of propofol anaesthesia on thoraco-abdominal volume variations during spontaneous breathing and mechanical ventilation (2011)
- Optimisation of positive end-expiratory pressure by forced oscillation technique in a lavage model of acute lung injury (2011)
- Positive end-expiratory pressure optimization with forced oscillation technique reduces ventilator induced lung injury (2011)
- Lung recruitment assessed by total respiratory system input reactance (2009)
- Low-dose oral midazolam reduces fear and distress during needle procedures in children with cancer (2009)
- Relationship between cerebral blood flow and oxygen metabolism, and extracellular glucose and lactate concentrations during middle cerebral artery occlsuion and reperfusion: a microdialysis and positron emission tomography study in nonhuman primates (2005)
- Haemodynamic and metabolic disturbances in the acute stage of subarachnoid haemorrhage demonstrated by PET. (2004)
- Increase of interstitial glycerol reflects the degree of ischaemic brain damage: a PET and microdialysis study in a middle cerebral artery occlusion-reperfusion primate model (2001)
- A comparison of three doses of sufentanil in combination withbupivacaine-adrenaline in continuous epidural analgesia during labour. (2000)
- A metabolic threshold of irreversible ischemia demonstrated by PET in amiddle cerebral artery occlusion-reperfusion primate model. (2000)
- PET i neurointensivvård och forskning. (1998)
- Preoperative weight loss, hypoglycaemia and ketosis in elective paediatric patients, preliminary results from a prospective observational study
- Active expiration may contribute to the reduction in end-expiratory volume during emergence from anesthesia and in the immediate post-operative period.
- The application of forced oscillation technique and self-mixing laser interferometers during anesthesia and mechanical ventilation.
