Anna Sundborger-Lunna
Universitetslektor vid Institutionen för cell- och molekylärbiologi; Strukturbiologi
- E-post:
- anna-sundborger-lunna@icm.uu.se
- Besöksadress:
- Husargatan 3
752 37 Uppsala - Postadress:
- Box 596
75124 Uppsala
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Nyckelord
- bar proteins
- cryo-electron microscopy
- membrane biophysics
- membrane remodeling
- mitochondrial dynamics
- neurodegeneration
- structural biology
Biografi
Dr. Anna Sundborger-Lunna received a M.Sc degree in Medical Biology from Linköping University in 2005 and a PhD in Neuroscience from Karolinska Institutet in 2010. She joined the laboratory of Dr. Jenny Hinshaw at the National Institutes of Health in 2010 to study the mechanisms of dynamin-mediated membrane fission using cryo-EM and various biochemical and biophysical methods. Dr. Sundborger-Lunna was recruited to the University of Minnesota Hormel Institute in 2016 to establish a new state-of-the-art cryo-EM facility and joined the Uppsala University ICM faculty in 2021 to establish a new cryo-EM facility and to continue her work on elucidating structure-function of membrane remodelling proteins and their roles in mitochondrial dynamics and cellular degeneration.
Forskning
Denna text finns inte på svenska, därför visas den engelska versionen.
Dr. Sundborger-Lunna's research focuses on unraveling the molecular mechanisms underlying membrane remodeling and cell death using a multi-disciplinary approach combining cryo-EM and complementary structural biology methods, biochemical/cell-free assays, and cell-based functional models and aims to answer an outstanding question in cell biology; How is the critical process of mitochondrial dynamics regulated and coordinated during neuronal cell death/survival signaling? The long-term objective of providing novel targets for therapeutic strategies to prevent neurodegeneration and to treat debilitating diseases like Parkinson’s and Huntingtin’s diseases.